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Yet another possibility is that BST2 uses AP1 to divert tethered virions to late endosomal compartments in antigen presenting cells, thus facilitating the presentation of viral antigens in the context of class II or class I MHC (Neil et al., 2006; Miyakawa et al., 2009; Moffat et al., 2013).
Although we failed to detect a direct difference in Bmp pathway activation at the protein level, Lrp4 might function by facilitating the presentation or integration of Gremlin1 into a signaling complex that mediates the activation of ureteric budding.
CD14 promotes immune activation by facilitating the presentation of LPS to TLR4 [ 10], which triggers interleukin- IL -12 and interleukin- IL -12d interleukin- IL -12oduction.
The enrichment of all factors on the outside or outer surface of fibroblasts suggests that FREM1 might be involved in facilitating the presentation of PDGFC to PDGFRα.
CCRC Objectives 1.Promote a culture of research among students in the High Schools in the Caribbean by facilitating the presentation by students of their research and awarding a prize to an Outstanding Child Researcher; 2.Promote a culture of research among teachers in the High Schools in the Caribbean.
It recycles through late endosomal/lysosomal compartments (Mahnke et al, 2000) facilitating the presentation of antigens targeted to DCs with antigen-bearing monoclonal antibodies in the presence of strong adjuvants such as CpG (Mahnke et al, 2005), polyinosinic-polycytidylic acid (Poly I C) (Trumpfheller et al, 2008) or anti-CD40 antibody (Bonifaz et al, 2004).
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