To facilitate the inference of GWAS in pharmacogenomics, we sought to undertake the mathematical integration of the pharmacodynamic (PD) process of drug reactions through computational models.
In summary, our study showed that over the wide taxonomic range of glires, datasets comprising whole mitochondrial genome sequences facilitate the inference of substitution rates, phylogenetic analyses and divergence estimates.
This landscape can be used to facilitate the inference of disease genes, thereby benefiting studies on pathology of diseases.
Degenerate positions in heterozygote sequences were scored using IUPAC nomenclature to facilitate the inference of allelic phase (see below).
More specifically, mathematical models can be used to facilitate the inference of malfunctioning reactions that lead to human diseases from clinical data.
The organization of the testis and the process of spermatogenesis are known in great detail for Drosophila melanogaster [ 12- 14], and some other drosophilids [ 15- 17], and they have features that greatly facilitate the inference of certain aspects of testicular architecture.
Extending the UNPBN approach to dynamic data, or using perturbation data or adding prior information, will further facilitate the inference of directionality in the causal relations for each cell subpopulation.
To demonstrate the capacity of the NovelFam3000 system to facilitate the inference of protein domain functions, we selected a set of 39 domain families for targeted experimental studies (Table 1).
In this way, the challenge is more than a simple verification, but is a curation and refinement process that looks to expand and maintain up-to-date biological knowledge as well as facilitate the inference of new relationships.
This result demonstrates that coexpression modules, at least the ones identified in this study, represent actual transcriptional coordination between genes, and can facilitate the inference of tomato gene function.
