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Hypothetically, bypassing the natural infection routes by delivering antigens directly to APCs may overcome the pathogen's naturally evolved evasion mechanisms, thus facilitating the induction of protective immune responses.
Overall, these results provide a mechanism for platelet activation of APC facilitating the induction of adaptive immunity in environments of cell injury.
Therefore, the usage of delivery system and/or immunostimulants is critically important in facilitating the induction of potent and long-lasting immune protection after mucosal vaccination.
DCs bring antigens to T cells and express costimulatory molecules, facilitating the induction of the immune response [ 22].
We show that Sp1 can redirect p53 towards a specific transcriptional program facilitating the induction of apoptosis.
Viral vectors, such as those based on adenoviruses or pox viruses (de Cassan & Draper, 2013), mimic a live infection by expressing antigens in situ after immunization, thereby facilitating the induction of strong T-cell responses, including cytotoxic T lymphocytes.
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This combination may facilitate the induction of therapeutic hypothermia in stroke victims.
AMPH paired with motor training facilitates the induction and retention of use-dependent plasticity.
Ikegaya, Y., Saito, H. & Abe, K. High-frequency stimulation of the basolateral amygdala facilitates the induction of long-term potentiation in the dentate gyrus in vivo.
Class I metabotropic glutamate receptor agonists do not facilitate the induction of long-term potentiation in the dentate gyrus of the rat in vitro.
Several lines of research are currently focusing on the development of different technologies to facilitate the induction and expansion of antigen-specific T cells.
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