PALB2 ('partner and localizer of BRCA2') was recently identified to play an important role in facilitating the function of BRCA2; nearly 50% of BRCA2 is associated with PALB2 and more than 50% of PALB2 forms a complex with BRCA2 [ 8].
Furthermore, ASC is capable of binding and facilitating the function of several other inflammasomes (such as NLRC4 and IFI16), though the relevance of this during pneumococcal infection is not evident [ 29].
Enhancing employment and income growth in the rural areas entails scaling up actions to improve the productivity of smallholder agriculture, promoting sustainable use of natural resources, improving rural infrastructure, research and communications, facilitating the functioning of markets and enhancing rural institutions.
In contrast, overexpression of the longest form of human wild-type tau (tau441) in mouse neuroblastoma (N2A) showed an anti-apoptotic protective function of tau phosphorylation, which likely inhibited competitively phosphorylation of β-catenin by GSK-3β, facilitating the function of β-catenin.
Furthermore, this study stresses the importance of localization as a factor that influences the function of ICP0 but also highlights the importance of identifying post-translational modifications or additional activities that facilitate the functions of ICP0.
Thus, one possible mechanism by which ZNF198-like proteins facilitate the functions of the LSD1 CoREST HDAC1-containing corepressor compLSD1 CoREST HDAC1-containinglize the LSD1–corepressor1 ternary complexesn chromatis.
Our position is that the ability of NS-398 to produce an anti-invasive effect on cancer cell lines is due to the down-regulation of prostaglandin production, which facilitates the functions of COX-2.
However, another unique feature of the T. brucei import machinery is that only a single member of the Tim17/22/23 protein family has been found in its genome, suggesting that a single TIM complex facilitates the functions of both TIM23 and TIM22 in the single mitochondrion of this unicellular parasite (Schneider et al. 2008).
Ideally, every economy would provide a range of institutions to facilitate the functioning of markets, but developing countries fall short in a number of ways.
