Sentence examples for facilitating the efflux from inspiring English sources

All these genes encode membrane proteins, consistent with their role in facilitating the efflux of organic acid anions.

Cellular Na overload and AP prolongation stimulate the reverse mode NCX facilitating the efflux of Na in exchange for influx of Ca [ 14].

Previous studies have shown that a decrease in blood glutamate concentration leads to a larger natural glutamate gradient between the brain and blood, facilitating the efflux of excess extracellular brain glutamate into the blood.

In addition, a plasma membrane ABC-type transporter facilitates the efflux of cholesterol and phospholipids onto HDL particles.

The ionophore facilitated the efflux of calcium from the cells.

Newer SGA have an inbuilt drainage channel to facilitate the efflux of gastric fluid and gas and allow the insertion of a gastric tube.

Notably, tet 38) also facilitates the efflux of antibacterial fatty acids, which promotes survival in an abscess environment and colonisation of skin surfaces [ 46].

Along with bile acids, MRP8 facilitates the efflux of E217β-glucuronide and E1S (151, 151), and it has also been shown to transport DHEAS in the canine kidney cell line MDCK (152).

Cyp46a1 (cytochrome P450, family 46, subfamily A, polypeptide 1) is the cholesterol 24-hydroxylase which catalyzes the oxidation of cholesterol into 24S-hydroxycholesterol to facilitate the efflux of cholesterol across the blood brain barrier [ 69].

ABCG2, the so-called breast cancer resistance protein (BCRP), is an ATP-binding cassette (ABC) drug transporter that facilitates the efflux of various tyrosine kinase inhibitors, including sunitinib, from cells.

ABCG2 was first detected in breast cancer-resistant cells and can facilitate the efflux of a variety of specific endogenous substrates, certain xenobiotics, and anticancer agents (such as Adriamycin/daunorubicin, 7-ethyl-10-hydroxycamptothecin, topotecan, and mitoxantrone), mediating multidrug resistance [ 7, 24– 26].