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Our results indicate that this combination therapy might be a promising strategy for facilitating the effects of erlotinib monotherapy by activating various networks.
The most likely explanation for this is that linopirdine depolarized the PASMC, thereby facilitating the effects of hypoxia, but the depolarization was too small by itself to activate sufficient Ca2+ influx for contraction (5).
Walter et al. [ 32] verified in the acute phase of injury (1 7 days) increased levels of IGFBP-1, -2, -3, -6 localized in injury responsive astrocytes, neurons, and cells of the monocyte lineage, probably facilitating the effects of IGF-1.
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Alcoholism is associated with Streptococcus pneumoniae, anaerobic organisms, and Mycobacterium tuberculosis; smoking facilitates the effects of Streptococcus pneumoniae, Haemophilus influenzae, Moraxella catarrhalis, and Legionella pneumophila.
These results indicate that the expression of the NR2B transgene in the cerebellar granule cells significantly facilitates the effects of VMT on motor learning.
Several studies in diverse organisms indicate that sirtuins may facilitate the effects of caloric restriction [ 34- 36].
In contrast, integrin induced changes in cell shape often function to facilitate the effects of cytokines.
Nuclear TCF4 labelling was observed in 46.7% of cultured OPCs, suggesting that it is the nuclear expression of TCF4 that facilitates the effects of Wnt3a on OL differentiation.
For example, we have seen that trait anxiety facilitates the effects of threat information, as does the child's rearing environment.
Although it is unclear by which mechanism F-actin rearrangement facilitates the effects of Rho-kinase on PI3-kinase/Akt and apoptosis, several mechanisms can be proposed.
It is hypothesised that the dry needling approach will decrease the pain and disability of chronic whiplash by reducing the sensory hypersensitivity and facilitate the effects of the exercise program.
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