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Middle-class activists are marching on Washington, calling and writing their representatives, suing in the courts, facilitating resistance schools at major universities, donating to the ACLU and Planned Parenthood ― and they're getting results.
Their clinical importance is in facilitating resistance to potentially lethal levels of quinolone.
Firstly, as a clear association between symptomatic infections with ESBL- Ent and recent travelling has been recorded [ 33], knowledge of high colonization rates in travellers might lead to an increase in the use of carbapenems, facilitating resistance development.
This increase in multidrug-resistance is not only associated with increased morbidity and mortality and higher cost, but with the need to use broader spectrum antibiotics to treat common infections, therefore further facilitating resistance development [ 1, 2].
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Like many multi-drug-resistant organisms, S. aureus contains antibiotic-modifying enzymes that facilitate resistance to a multitude of antimicrobial compounds.
In this review, we indicate examples of alternative signal pathways for recent anticancer drugs, and the use of original, Python-based software to systematically identify signaling pathways that could facilitate resistance to drugs targeting a particular protein.
We hypothesized that these signaling pathways may facilitate resistance.
Generally, restricted antibiotic use and lower animal densities may facilitate resistance prevention.
A single opening of a pump facilitates resistance to quinolones, beta-lactams, tetracycline, and chloramphenicol among the drug efflux (9 ).
Combination therapies have revealed how resistance mechanisms can facilitate resistance to other antibiotics or, in some cases, reduce the likelihood of resistance to a second antibiotic.
Interestingly, it has already been hypothesized that autophagy might facilitate resistance against the small molecule HER2 receptor kinase inhibitor Lapatinib in HER2-positive breast cancer cells.
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CEO of Professional Science Editing for Scientists @ prosciediting.com