Sentence examples for facilitating receptor internalization from inspiring English sources

Pim-1 phosphorylates Serine339 on CXCR4 facilitating receptor internalization and re-expression on the cell surface.

It was suggested that there may be a requirement for a positively charged amino acid to facilitate receptor internalization.

Earlier studies have demonstrated that ligand-activated CXCR4 binds β-Arrestin 2 (also known as Arrestin 3), a process that facilitates receptor internalization [27], [41].

Finally, it may also be that the interaction of the HEMADO-bound mutant receptor and β-arrestin2 in the W243F cell line (in the absence of β-arrestin2 overexpression) is normally transient and not long enough to facilitate receptor internalization.

In addition, AT2S behaved as an agonist for sst2 and sst3 since it stimulated receptor internalization.

Binding of 68Ga-PSMA-HBED-CC leads to receptor internalization and tracer accumulation.

In contrast, granisetron and ondansetron showed minimal to no effect on receptor internalization or prolonged inhibition of receptor function.

Agonist-induced receptor activation is terminated with the recruitment of β-arrestin, which leads to receptor internalization.

The low temperature inhibits receptor internalization.

Agonists at MOP cause fast receptor internalization with internalization half-times 2 5 min (Fig. 1D).

Receptor internalization was determined on fixed permeabilized specimens as follows.