Sentence examples for facilitating its interaction from inspiring English sources

Finally, KRIT1 could also promote the stabilization and function of FoxO1 by facilitating its interaction with β-catenin.

S-nitrosation did not interfere with the SUMO conjugating activity of Ubc9, but promoted Pias3 degradation by facilitating its interaction with tripartite motif-containing 32 (Trim32), a ubiquitin E3 ligase.

Reciprocally, CHIP ubiquitinates BAG3 further facilitating its interaction with p62 eventually resulting in engulfment by phagophore) [ 76, 77].

One possible mechanism is that SIRT1 deacetylates TORC1, facilitating its interaction with CREB and transcription of BDNF, a neurotrophic factor that is protective in HD.

YY1 negatively regulates p53 by facilitating its interaction with Mdm2 (and its human orthologue, Hdm2), leading to p53 ubiquitination [ 53, 54].

Altogether, these results suggest that MT2A silencing in osteosarcoma cells does not significantly affect cell viability but can enhance sensitivity to drugs such as doxorubicin by facilitating its interaction with DNA.

These co-chaperones assist Hsp90 by modulating its ATPase cycle and by facilitating its interactions with various client/substrate proteins [ 8- 10].

Although the NES seems dispensable for HSV-1 lytic replication in the present study, it might be important for certain ancillary functions that could facilitate its interaction with the host.

Presence of both ether and ester group in the alkyl chain facilitates its interaction strength.

Recently, Axin was found to be phosphorylated by CDK5, and this phosphorylation facilitates its interaction with GSK3, which plays an essential role for axon development (Fang et al., 2011).

However, questions still remain about the three-dimensional arrangement of the pharmacophoric groups of AEA that facilitate its interaction with cannabinoid receptor, a member of transmembrane G-protein coupled receptors (GPCRs).