Sentence examples for facilitating gene repression from inspiring English sources

It goes without saying that TFs also play other fundamental roles, such as facilitating gene repression, setting chromatin boundaries and maintaining 'primed' transcriptional states 16– 16.

Histone ADP-ribosylation facilitates gene transcription by directly remodeling nucleosomes.

Positioning a promoter or gene near the telomere (or indeed anywhere at the nuclear envelope) in a strain that has functional telomere anchoring facilitates stable gene repression, as long as the targeted reporter contains Sir nucleating elements, such as silencers or protosilencers [ 61, 77- 79].

Rosa, S., Duncan, S. & Dean, C. Mutually exclusive sense-antisense transcription at FLC facilitates environmentally induced gene repression.

Each of these critical components of NR function were essential in demonstrating that receptor "agonists" or receptor "antagonists" facilitate molecular interactions necessary for target gene induction or gene repression in vivo.

The removal of H3K27ac by the NURD complex facilitates the recruitment of PRC2 and accumulation of H3K27me3 at promoters leading to gene repression 148.

Indirectly, it can facilitate the binding to methylated DNA of methyl-CpG-binding domain proteins, which can mediate gene repression through interaction with histone-modifying enzymes [ 28].

Hence, gene repression mediated by the unliganded RARγ2-co-repressor complex constitutes a novel mechanism to regulate and facilitate the correct expression levels and spatial restriction of key genes that maintain the caudal progenitor pool during axial elongation in Xenopus embryos.

In quiescent cells, RB family proteins bind to E2F transcription factors, facilitating repression of genes that are necessary for the transition into the S phase of the cell cycle.

Programmable gene repression by ddCpf1/crRNA.

Multiplex gene repression with ddCpf1 and a crRNA array.