Sentence examples for facilitating cell motility from inspiring English sources

Here, we show the structure of BdcA in complex with NADPH and confirm that NADPH binding is requisite for BdcA facilitating cell motility and increasing biofilm dispersal.

Knockout animal models have clearly demonstrated the critical role of gelsolin in facilitating cell motility [ 26- 30].

Hakai induces E2-dependent ubiquitination of the E-cadherin complex followed by endocytosis, disrupting cell cell adhesions and facilitating cell motility under physiological conditions.

The role of this integrin evolves, however, under pathological conditions when β4 is rendered signaling competent and assumes an active role in initiating various signaling cascades and facilitating cell motility.

Also, versican enhances breast cancer cell metastasis in mouse breast cancer cell lines, not only through facilitating cell motility and invasion but also by inhibiting preosteoblast cell growth and differentiation which supply favourable microenvironments for tumor metastases [ 132].

In the absence of ligand, EphA2 facilitates cell motility by coordinating signaling from a variety of RTKs via growth factor mediated activation of AKT [10], which initiates AKT-dependent EphA2 phosphorylation residue S897.

Its activities on binding and microtubule polymerization facilitate cell motility by remodelling the microtubule cytoskeleton [ 58].

These findings suggest that CCN3, through its interaction with S100A4, might alter cytoskeletal organization and facilitate cell motility.

ENPP2 facilitates cell motility and progression and is related to the invasion of ductal breast carcinomas [ 75].

To facilitate cell motility, invading cells need to change their cell-cell adhesion properties, rearrange the extracellular matrix (ECM) environment, suppress anoikis, and reorganize their cytoskeleton [ 3].

33 Interestingly, EMT is also a feature of many cancers, in which it facilitates cell motility and thus contributes to cancer cell invasion and metastasis.