E-cadherin, an integral part of adherens junction, maintains the integrity of epithelial cells by facilitating cell-cell adhesion [ 32].
These include facilitating cell-cell matching and epithelial sheet adherence during dorsal closure in Drosophila,, transmitting signals such as Delta-Notch and Sonic Hedgehog signaling between non-neighboring cells,, inducing cell shape changes required for preimplantation embryonic development by providing tension and positioning nuclei in nurse cells during oogenesis in Drosophila.
Here, we report a method for engineering MCTS using a transient inter-cellular linker which facilitates cell-cell interaction.
The cell wall of C. albicans contains many different carbohydrates and proteins that come into contact with epithelial cells and facilitate cell-cell interconnections [10], [11].
Cells were centrifuged for 1 minute at 335 g to facilitate cell-cell contact, and incubated for 4 hours at 37°C.
The intestinal epithelium is characterised by tight and adherent junctions that facilitate cell-cell contact and restrict the paracellular transport to small hydrophilic molecules.
Integrins are cell surface proteins that facilitate cell-cell adhesion and interaction.
It was hypothesized that PBP2a facilitates cell-cell interactions in the formation of MRSA biofilm [ 8].
Adhesion molecules are surface antigens that facilitate cell-cell and cell-extracellular matrix (ECM) interactions, through their respective receptors.
This regulated association would, for example, facilitate cell-cell junction remodelling during wound healing or in response to inflammatory stimuli.
Regulated F-actin/AJ interactions would, for example, facilitate cell-cell junction remodeling during wound healing, in response to inflammatory stimuli, or to accommodate leukocyte extravasation.
