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This could be related to the SF amino acid sequence that acts as cell receptors facilitating cell adhesion and growth.
In addition to facilitating cell adhesion, promoting cell growth, and allowing the retention of differentiated cell functions, the scaffold should be biocompatible, biodegradable, highly porous with a large surface/volume ratio, mechanically strong, and malleable.
In this context, plasmin is suggested to initiate intracellular signaling pathways as well as to activate extracellular matrix (ECM) degrading enzymes ultimately facilitating cell adhesion and migration [4] [6].
Many studies have also shown that integrin-linked kinase mediate cytoskeletal changes and cell migration via activation of Akt (Qian et al, 2005) and that Akt is necessary for the recycling of integrins from the lagging edge to the leading edge (Roberts et al, 2004), facilitating cell adhesion and migration.
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Thus, it is reasonable to deduce that PSC-SN-promoted trans-migration of cancer cell by providing adhesive molecule(s) to the interface of inserts, which in turn facilitated cell adhesion and then accelerated the motility.
Surface coating and pore formation were achieved to facilitate cell adhesion and cell growth.
The hydrogel scaffolds were further surface coated to facilitate cell adhesion and cell growth (Landers et al. 2002).
Collagen type I was immobilized onto the scaffolds to facilitate cell adhesion.
Pinto, et al. reported that only low concentrations of GO may be incorporated safety in PLA to facilitate cell adhesion and proliferation [6].
In order to culture the cells on the SPEs surfaces the working electrodes were coated with poly-l-lysine to facilitate cell adhesion.
Initially, the proteins were analyzed for molecular weight and amino acid content, as well as their ability to facilitate cell adhesion and proliferation.
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