Exact(2)
Although the various single base lesions require different lesion-specific glycosylases, APE1 is common to BER and incises the backbone of the DNA strand and facilitates gap filling by DNA Polβ.
In theory, we might make the initially counterintuitive suggestion that those species that have long life cycles may benefit most from the dispersal enhancing selection pressure that facilitates gap crossing as they experience time and thus the rate of climate change faster (the generation effect).
Similar(58)
The end sequence data facilitated gap closure as well as accurate reconstruction of the entire genome.
We have developed a Cytoscape plugin to facilitate gap closing for high-throughput sequencing data from microbial genomes.
The library inserts comprised homologous regions to the BamHI/NotI-digested pYD1 backbone on both sides in order to facilitate gap repair driven homologous recombination in S. cerevisiae.
To facilitate gap closure and assembly validation, contigs were mapped to the A. pasteurianus IFO 3283 genome by means of the r2cat tool [ 20, 69].
We think that this whole genome optical map will greatly facilitate gap closure efforts and guide correction of misassemblies to provide an accurate and completely sequenced model for plant genome research – especially for cereal genomes.
Our results also suggest that additional genetic markers and an increase in BAC library coverage would facilitate gap closure and the mapping of structurally important repetitive regions of chromosomes.
Sanger-based sequencing was employed to facilitate the gap closure and to amend the low-quality regions (score < 60).
The rapid diffusion of essential signaling molecules, such as cyclic AMP, inositol 1,4,5-tri-phosphate, ions, and nutrients between adjacent cells, is facilitated by gap junctions (Evans and Martin, 2002).
The HhH motif is conserved in other members of the X-family DNA polymerases and is believed to facilitate DNA gap binding.
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