Thus, the reverse binding mode of 15 facilitates a network of hydrogen bonds in the inner binding pocket connecting the Ser117 residues of all subunits, the nearby water molecules, and the carboxylate substituents of the inhibitor (Figures 7a and 7c).
The carboxyl group simultaneously interacts with Ser117 and Thr119 residues of both HBP3 and HBP3' and facilitates a network of hydrogen bonds in the inner binding pocket connecting the Ser117 residues of all subunits, the nearby water molecules, and the carboxylate substituents of all the inhibitors.
In particular, we hope to facilitate a network among students pursuing in-depth research in one or several disciplines, whether quantitative or qualitative in focus, to generate a larger interdisciplinary discussion concerning sustainable development.
As a result of this success, Amazon has doubled down on the effort, launching an investment fund for companies to utilize their Alexa technology (the voice assistant used in the Echo) and they're hard at work facilitating a network of Alexa "Skills" developers to create simple tasks that Alexa - and by extension, the Echo - can perform.
The organization was an interdenominational non-profit that facilitated a network of groups and other organizations which worked to "help" people change their sexual orientation to heterosexuality (or, at least, to limit their "homosexual desires").
The dual roles facilitated a network of academic and decision-maker relationships from which the collaborative research team was built.
Business relationships with network service and infrastructure providers, particularly those that offer high bandwidth connectivity to the business market, serve to give jSpan a strategic advantage by facilitating a network connection to potential jSpan customers.
Furthermore, the recently discovered T-helper-17 proinflammatory cytokines, present in syno-vium samples, are associated with the migration, differentiation and maturation of inflammatory cells, and they facilitate a network of interactions between all components of the immune response.
Today, AFC facilitates a vast network of agencies and services, serving thousands in Chicago and throughout Illinois.
Prosecutors contended that Mr. Weinig and his partners helped facilitate, through a network of couriers, cash pickups of drug money from the street.
If universities ensured they were members of their local social enterprise network — like us at SEWM CIC and the national body Social Enterprise UK — we could assist in facilitating such a network.
