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For example, is this simply due to the conservation of an ancient pri-miRNA gene pair structure or is there a purpose for this overlapping gene structure that facilitates a complex and interactive physiological regulation of mammalian miRNA expression?
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To facilitate a complex design process without losing fidelity, a graph-based formalism, namely General Environment Model (GEM), is proposed to be applied to model such an environment.
However, a new and innovative conceptual framework, known as social quality theory, facilitates a more complex and complete understanding of the SDH, with its focus on four domains: social cohesion, social inclusion, social empowerment and socioeconomic security, all within the same conceptual framework.
The process involves regulatory oversight, compliance checks and other layers of protection, and is facilitated via a complex series of service agreements.
The process of gene-amplification involves initiation of DNA replication at specific points in the genome, facilitated by a complex of proteins which recruit the machinery necessary for DNA synthesis [ 58].
Once Ago2 is loaded with the double-stranded siRNA, only one strand (guide) is retained and the other strand (passenger) gets removed and degraded (Matranga et al, 2005; Rand et al, 2005; Leuschner et al, 2006; Miyoshi et al, 2010), which can be facilitated by a complex consisting of TRAX and translin (C3PO, component 3 promoter of RISC) (Liu et al, 2009; Ye et al, 2011).
The CDK1-cyclin A complexes then facilitate the progression to G2 phase.
Cell culture experiments suggested that upon ligand stimulation, an extracellular cleavage close to the membrane facilitates a presenilin complex-dependent cleavage that releases the intracellular domain from the cell surface [5], [9] [11].
The chelating action of citric acid facilitates the formation a complex intermediate of Mn2+ and citrate ions, which finally results a 3D MRGO3/RGO (MRGO) composite with high electrical conductivity (∼1056 S m−1), good surface area (59 m2 g−1) and high pore volume (0.3 cm3 g−1).
A technique merging rotational spectroscopy with mass spectrometry facilitates analysis of a complex isotopic mixture.
The results from these studies clearly facilitate a more complex and comprehensive understanding of existing problem.
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CEO of Professional Science Editing for Scientists @ prosciediting.com