Given the clinical significance of BCR-ABL in leukemia treatment, we sought to investigate the roles of BCR-ABL in CML and its relationship with telomerase regulation, in order to facilitate in the development of better anti-CML drugs.
Substantial advances have been made in elucidating the pathogenesis of SSc, which has been facilitated in part by the development of more appropriate animal models.
To address the need to provide a comprehensive resource to facilitate research in the development of an ECF vaccine and comparative Apicomplexan genomics, TparvaDB was developed to provide a unified platform for all genome and related T. parva data.
Endothelial dysfunction is both an early marker of vascular diseases and a facilitating factor in the development of atherosclerosis [ 14- 16].
The proposal for a multitargeted, TCS-mediated antibiotic may find inspiration from these molecules to facilitate progress in the development of antibacterials with a novel mechanism of action.
Although CXCL10-mediated NK cell trafficking does not appear to be a crucial factor in facilitating the development of shock in the CLP model, CXCL10-induced NK cell activation may play a role.
In this study, we validated a specific GEI model in facilitating the development of motor skill learning in the mouse and provided valuable insight regarding molecular/neuronal basis for motor learning from three aspects.
Transposons, genomic islands and point mutations are the main contributors to the plasticity of the A. baumannii genome and play critical roles in facilitating the development of antibiotic resistance in the clinical isolates.
The importance of promoting intrapartum ultrasound examination is related to its high accuracy in predicting vaginal delivery and in facilitating the development of a decision-making strategy during labour [ 13].
