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This process is facilitated by complement, the activation of which has been proved also in MAS [ 11].
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Our analysis strongly suggests that, similarly to the above-mentioned pathologies, the inflammatory damage to optic nerve in POAG is facilitated by excessive production of complement proteins and clusterin by the reactive ONHAs.
The actual destruction of microbes involves phagocytosis by granulocytes and macrophages, and this is greatly facilitated by the participation of the complement system.
The search for occurrences on forward and reverse strands is facilitated by also adding the reverse complement of all query sequences to the same tree.
The work may also be facilitated by hiring an outside consulting firm, complementing ICU or hospital manpower resources.
The nanoparticle clearance is facilitated by the opsonization of blood components and complement proteins on the particle surface (31).
Phagocytosis is the binding and ingestion of bacteria which can be facilitated by opsonization of the microbial surfaces with antibody and/or complement.
Identification of the phenotype-causing mutation among the entire complement of sequence variants can be significantly facilitated by whole genome sequencing of two distinct alleles of the same locus.
When phagocytosis is facilitated by opsonins, the ingestion occurs via receptors to components of complement or to FcγIgG (CR1, CR3 and FcR) in neutrophils/monocytes that will recognize their respective ligands during the process of phagocytosis [ 25, 30, 31].
We interpret the relatively fast turnover rate for tRNAs to be facilitated by the high degree of functional redundancy in the tRNA gene complement in any single genome.
The extension of these studies to other Genotype A and B isolates will be facilitated by in-depth sequences of the GS and DH isolates to complement the currently available WB sequence.
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