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A computer simulation based on combination of AChE kinetic data (inhibition, reactivation, aging) with OP toxicokinetics and oxime pharmacokinetics allows the calculation of AChE activities at different scenarios and may facilitate to define effective oxime concentrations and to optimize oxime dosage in OP poisoning.
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Then, the population-based atlas facilitates to define the target (the point with the highest probability), while the anatomical atlas (containing target's anatomical neighborhood) the trajectory to it.
Datamarts also help to define group of users, facilitating the potential to define their specific needs further.
These studies performed in animals will facilitate efforts to define in the near future the more rational design of CMS doses in humans, especially in the ICU setting.
We anticipate that CFPS-ME will facilitate efforts to define, manipulate, and understand metabolic pathways for accelerated DBT cycles without the need to reengineer organisms.
We established a unique HSV-2 macaque model that will likely facilitate research to define how HSV-2 increases HIV transmission, and enable more rigorous evaluation of candidate anti-viral approaches in vivo.
It will be helpful to collect such questions and evaluate their usefulness to facilitate efforts to define fitness correlates.
Pinpointing these sites will facilitate studies to define how differential 14-3-3 14-3-3 14-3-3 the PAK kinase family contregulation cofrdinathen of cell morPAKlogy and other regulatory processes (40, 41).
The hospital leadership should promote accountability by facilitating professionals to define what practices constitute quality care and subsequently foster development of goals and standards of patients' care at all levels.
We predict that similar analyses will facilitate ongoing efforts to define molecular mechanisms in other stem cell and developmental paradigms.
Alternatively, a larger sample size may facilitate the ability to define a closer association between promoter methylation status and expression in these genes.
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