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The method is designed for the application of continuous force disturbances that facilitate interaction of the limb with the environment.
Since CYLD failed to deubiquitinate RIP in the absence of optineurin, it is likely that optineurin acts as an adaptor to facilitate interaction of CYLD with RIP.
Hence, one way ClpX may promote translation of the rot and spa mRNAs is by, directly or indirectly, unfolding the stem-loop structures to facilitate interaction of these mRNAs with the translational apparatus.
In the simplest model proposed for the role of lipid rafts in GPCR signaling, lipid rafts are viewed as signaling platforms that facilitate interaction of different molecules involved in a specific signaling pathway with a higher density [15].
In general, transcriptional regulators activate the expression of genes in such a way that they facilitate interaction of the RNA polymerase with the respective promoters.
This initial cleavage, in turn, would facilitate interaction of the other chains with the MMP catalytic domain, thus triggering the collagenolytic process.
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Folding homology between DN and DC subdomains further renders the layer an approximate sixfold symmetrical architecture, which may facilitate interactions of the docking layer with the homo-hexamer of the adapter AcrA in the assembled complex (Jeong et al. 2016).
These effector proteins facilitate interactions of the SCV with the host cell endocytic pathway leading to maturation of the SCV, and also serve to position the SCV towards the Golgi where replication is initiated.
This parallel adsorption orientation also facilitates interaction of π − electrons of the anthraquinone nucleus and the hetero-atoms with the metal surface.
We draw empirical examples from the Innovation Hub at Groote Schuur Hospital in Cape Town to illustrate that innovation does not take place in an institutional vacuum, but requires space that facilitates interaction of different players.
When the viral protein accumulates to a threshold in the presence of NS3 protein, La-mediated enhancement of translation is inhibited, and La protein promotes the replication of HCV RNA by facilitating interaction of the 5′- and 3′-UTRs (Ray and Das, 2011).
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