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Our data will facilitate deciphering molecular ecology, patho-adaptation of F. tularensis to the arthropod vector and its role in bacterial ecology and patho-evolution to infect mammals.
Our data will facilitate deciphering the ecology, and patho-adaptation of F. tularensis to the arthropod vector and its role in bacterial ecology and patho-evolution to infect mammalian cells.
With continued advances in genome biology, the evolutionary genomics approaches undertaken here will further illuminate the lineage-specific distribution of Ca2+ channels and transporters at the genomic scale and greatly facilitate deciphering the Ca2+ signaling codes in a species- and/or tissue-specific manner.
More importantly, numerous O-GlcNAc sites have also been mapped, which not only significantly facilitate deciphering the crucial roles of O-GlcNAc on individual proteins in various biological processes, but also provide us a much deeper insight on how this modification closely interplays with many other PTMs (especially phosphorylation) in complex molecular networks.
A total of 22,295 sequences has been successfully annotated with GO terms based on the known sequences, and part of unique sequences are involved in the flavonoid metabolic pathway, which would facilitate deciphering the molecular mechanism of secondary metabolism in Epimedium.
To facilitate deciphering underlying transcriptional regulatory circuits in mouse embryonic stem (ES) cells, recent ChIP-seq data provided genome-wide binding locations of several key transcription factors (TFs); meanwhile, existing efforts profiled gene expression in ES cells and in their early differentiated state.
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Knowledge of these details might undermine randomisation by facilitating deciphering of the allocation sequence.
Then it might possible to establish an insertion resource that systematically targets rice genes by simultaneously creating both a knockout and a reporter line using these technologies that will greatly facilitates the deciphering of the function of all rice genes by 2020.
These cDNA sequences permit in silico cloning of numerous genes and will facilitate studies aimed at deciphering the roles of cognate genes expressed in the nervous system during neural development and metamorphosis.
These findings exemplify how functional genomic approaches may facilitate the efforts to decipher genetic mechanisms underlying clinical features of ASD and other heritable disorders.
This method in future could be developed as a highly sophisticated genotyping system based on integrated genome analysis approaches to correctly identify and track leptospiral strains and is expected to greatly facilitate epidemiology of leptospirosis apart from deciphering the origins and evolution of leptospires in a global sense.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com