Sentence examples for facilitate compound from inspiring English sources

Collectively, these results demonstrate the models' ability to discriminate between active and inactive compounds, suggesting that the models may be used to pre-screen compounds to facilitate compound optimization and to design novel inhibitors for drug development.

The power of the zebrafish model lies in its ability to accommodate genetic screens to identify responsible or modifier genes and also facilitate compound screens to identify new chemicals that influence developmental processes and signaling pathways.

Previously, several groups have utilized computational predictions of metabolite biotransformation to facilitate compound identification from MS data [ 10, 12, 13].

Global positioning system (GPS) coordinates were taken at the entrance of each compound to facilitate compound identification and follow-up on blood and environmental testing results.

For experiments involving sulfated bile salts or steroids, human SLC21 was co-transfected at 10 ng/well to facilitate compound uptake.

A thin slice was removed from the base of each berry by cutting horizontally through the brush area to facilitate compound absorption and the modified berries were placed on agar.

In our approach, the use of computational chemoinformatics enabled the generation of hit compound network similarity graphs that grouped compounds based on chemotypes, facilitated compound target and off-target prediction, and identified analogs of validated inhibitors with the potential to be more potent, more specific, or less toxic.

For both the use cases above, we present here a set of KNIME workflows, which facilitate rapid compound novelty checks by using the UniChem Connectivity Search web services.

To facilitate predictive compound design in a better way than it is currently possible via directed structural modifications, we also plan to incorporate biological activities and ADME/Tox properties into the morphing process.

In summary, the approach described herein might facilitate lead compound identification and repurposing of drugs.

Here, we demonstrate how this well-curated database facilitates compound set design, tool compound selection, target deconvolution in phenotypic screening, and predictive model building.