Sentence examples for facilitate binding to from inspiring English sources

The estradiol portion of the molecule was designed to facilitate binding to steroid receptors in malignant cells, which is then followed by the intracellular release of the nitrogen mustard alkylating moiety.

In addition, chimeric fusion proteins have been engineered that incorporate in a single polypeptide chain heterologous protein domains which facilitate binding to plasmid DNA, specific recognition of target cells, induction of receptor-mediated endocytosis, and DNA transport through intracellular compartments.

Thus the BEK receptor, like FLG, also requires an interaction with heparan sulfate proteoglycans to facilitate binding to its ligands.

This reflects the fact that different HS structures are required to facilitate binding to VEGF165.

These adhesins facilitate binding to various matrix proteins or host cells [29].

Most antimicrobial peptides are cationic to facilitate binding to anionic bacterial membranes.

MDP bind to NALP3 thereby facilitating binding to ASC (apoptosis associated speck-like protein containing a CARD) by a pyrin domain (PYD -PYD interaction.

The Ser216 phosphorylation of CDC25C on the other hand, attracts members of the 14-3-3 14-3-3 14-3-3 familytates binding to other proteins such as Chk1, Chk2 and c-TAK1, that can bind to and relocate CDC25C to the cytoplasm [ 27].

In sea anemone, small and basic α-pore forming actionporin proteins have a phosphocholine binding site which facilitates binding to the cell membrane and formation of pores, a feature that they share with toxins such as diphtheria and anthrax111.

Further analysis indicated that amino acid isoleucine (99), aspartate (102) and lysine (104) are anchor residues facilitating binding to HLA-DR3 molecules.

In order to enhance target specificity, many drug-loaded materials are conjugated or coated by iron binding protein transferrin/apotransferrin for recognition and facilitating binding to cancer cells [21] [24].