Sentence examples for facilitate alterations from inspiring English sources

Microenvironmental changes that facilitate alterations in cell cycle arrest, apoptosis, cell immortalization, and cell adhesion warrant special attention.

This will facilitate alteration and evolution of functional centers in the O-23S rRNA not possible on the endogenous 23S rRNA.

Our data provide evidence for evolutionary diversification among minicollagens, which probably facilitated alterations in the morphology of the nematocyst wall and tubule.

TNFα facilitated alterations in other inflammatory mediators in PNMEC cultures are anticipated and remain to be established.

Interaction of the peptide with putative intracellular protein partners may be facilitating alteration of innate immune signaling pathways, overall resulting in the modulation of inflammatory responses by IDR-1002 in synovial fibroblasts.

Neither segmental duplication, nor any others, spans the amplified region in such a way that duplicons could facilitate the alterations observed here.

Accordingly, the choice of studies selected for determining the median total As value and/or the possibility that we did not obtain all the literature values could facilitate an alteration in the total As intake.

Moreover, regardless of mechanism, our data provide strong evidence for consideration of BORIS as a dominant controlling factor for facilitating epigenetic alterations associated with coordinated demethylation and reactivation of target genes that are of high value as potential therapeutic and diagnostic targets for NSCLC, HNSCC, and other tumors.

Gene synthesis technologies are an important tool for structural biology projects, allowing increased protein expression through codon optimization and facilitating sequence alterations.

This allowed the C-terminus of α-helix 6 to move away from the active site, thereby in turn facilitating the alterations in the orientation of the C-terminal helix).

It is widely accepted, however, that epigenetic alterations are a prerequisite of virtually all tumors and that epigenetic alterations facilitate the accumulation of further genetic modifications that result in cancer progression through clonal expansion of cells with a resulting proliferative advantage (35).