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Chamilos, G. et al. Drosophila melanogaster as a facile model for large-scale studies of virulence mechanisms and antifungal drug efficacy in Candida species.
Caenorhabditis elegans is well established as a facile model to decipher the genetic factors mediating pathogen-host interactions.
The inhibition of free radical generation can serve as a facile model for evaluating the activity of anticancer agents.
As cotton fibre contains a large population of single epidermal cells it provides a facile model for comparative evolutionary genomic analysis [ 17- 19, 21, 22].
These observations prompted a facile model in which Gpr1 serves as a receptor for glucose, which upon binding the ligand, stimulates activation of Gpa2, which in turn stimulates adenylyl cyclase.
Since retinoids and protease inhibitors suppress the expression of the ras oncogene in NIH 3T3 cells, NIH 3T3 cells may serve as a relatively facile model for finding and measuring chemopreventive agents that interfere with the carcinogenic process.
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Only a handful of gene regulatory interactions have been characterized experimentally [ 3- 8] (reviewed in [ 9]) – such studies are generally more difficult than in comparatively facile models such as yeast.
"To facilitate the translation of more personalized therapeutics, we require investigators facile with model systems, informatics, principles of drug action, quantitative signatures of drug exposure, and both mechanism-based and unbiased readouts of drug effects," they write.
To better understand functional implications of Pak1 nuclear import, we turned to zebrafish embryos as a facile vertebrate model system.
In summary, the single-line command facile.pl -rx model; xppaut model.ode -silent; facile.pl -aA output.dat model builds both the C model expected by AUTO and an XPP simulation file.
Colorectal cancer (CRC) is a leading cause of death in the developed world, yet facile preclinical models that mimic the natural stages of CRC progression are lacking.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com