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Faced with this difficulty, Elan has had to get creative in order to challenge Royalty Pharma's bid, which the pharmaceutical company says "significantly undervalues Elan".
Faced with this difficulty, Cleanthes insists that contrary to all that Philo and Demea have claimed, we must allow that there is more happiness than misery, more pleasure than pain, in this world.
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Faced with the difficulty of directly assessing a nominee's talents, we try to make do with proxies.
When faced with the difficulty of supplying Paris, businesses adopt strategies that impact the surrounding municipalities.
However, we are faced with the difficulty of regularity of weak solutions of Eq. (1.1), that is, (y' ) generally does not belong to (H^{2}_{0}) as notified before.
Forest managers are faced with the difficulty of promoting multiple ecosystem services (ES) with an incomplete understanding of the complex ways these ES interact.
Modelling soil bioturbation by soil engineers is of great importance although it is faced with the difficulty to describe the soil physical environment.
Recently, however, because of the limited area of the launching pad of the SBC, we have been faced with the difficulty of safely launching large balloons.
The reader is, therefore, faced with the difficulty of choosing for reference.
Once results of microarray experiments are reproduced, scientists and regulators are still faced with the difficulty of interpreting genomic signatures.
Immunization in humans has always faced with the difficulty of identifying safe adjuvants that do not generate unwanted side effects.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com