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The phrase "faced a major setback" is correct and usable in written English.
It can be used when describing a significant obstacle or difficulty encountered in a process, project, or situation. Example: "The team faced a major setback when their primary funding source was unexpectedly withdrawn."
Exact(2)
After a season of progress under the care of Dani, TK faced a major setback in last season's finale of "Necessary Roughness" (Wed., 10 p.m. ET on USA).
The company said that the new enhancements would allow "citizen scientists" to contribute to the important work of planet discovery, which faced a major setback after an equipment failure derailed NASA's own planet discovery mission.
Similar(55)
However she faces a major setback when bad weather threatens to derail her planned trip to Dublin.
The emergence at the border between Thailand and Cambodia of parasites resistant to the antimalarial drug artemisinin caused concern that global malaria-control efforts could face a major setback.
"In the face of this unpredictable change around the Arab world, Turkish foreign policy is facing a major setback," said Sami Kohen, a columnist for Milliyet, a daily newspaper in Turkey.
The plan could face a major setback if Justice Kornreich were to rule that it had to be taken back and submitted to uniform land use review, a process that would require it to be approved by the local community board, the City Planning Commission and possibly the City Council.
So is Sky facing a major regulatory setback to its business?
Could you tell me about a major setback you've faced and how you conquered it?
United Nations human rights experts called the pardon an appalling "slap in the face" for his victims and a major setback for the rule of law.
The boycott lasted a year and was a major setback for polio eradication.
On the face of it, the delay announced this morning looks to be a major setback for the chief executive of Sony, whose goal has been to revive the company's consumer electronics division.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com