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"face serious challenges" is a correct and usable phrase in written English.
You could use it in a variety of contexts to refer to different kinds of difficulties that someone or something might encounter. For example, you could say, "As a small business owner, I faced serious challenges when trying to grow my customer base."
Exact(60)
Spain, Europe and the world itself face serious challenges in the coming years.
Current electronic network-on-chip (NoC) designs face serious challenges, such as bandwidth, latency and power consumption.
Most developing countries face serious challenges that are already being exacerbated by climate change-related extreme weather events.
Its relations with the emerging world are about to face serious challenges, and development aid would be a positive response.
But the new government does face serious challenges, and the closeness of this election should be a wake-up call.
"The NHS in Scotland is not perfect and we still face serious challenges with waiting times and patient outcomes.
Especially the agricultural sector will face serious challenges, and communities may struggle to keep up drinking water supply.
None of the state's Democratic House incumbents face serious challenges Tuesday, or from Republicans in the fall.
And many could face serious challenges from a conservative, Tea Party activist if they vote for a compromise that includes a tax increase.
Any lawsuit against the drugmakers, however, could face serious challenges because the medications at issue were approved by the Food and Drug Administration as safe and effective.
"Recent events have reminded us that the U.S. economy and U.S. banks still face serious challenges ahead," Mr. Gruenberg said in the statement.
More suggestions(18)
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com