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It is characterized by many phenotypes, including wide anterior fontanel, frontal bossing of the face, depressed nasal bridge, along with the 4 classic phenotypes contained in the name of the syndrome.
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With companies already facing depressed earnings because of the strong dollar and higher costs, the sales fall-off forced the industry into painful actions.
When viewing negative emotional faces, depressed patients have greater amygdala activation but also reduced coactivation of the dorsal anterior cingulate and increased coactivation in the subgenual cingulate [ 42].
Physical abuse was positively correlated with amygdala responsiveness toward sad faces within depressed patients.
Each stimulus will appear on the screen for 2 seconds and for each facial trial adolescents will be asked to indicate the gender of the face by depressing one of two keys on a button box.
He had long face, broad forehead, depressed nasal root, midface hypoplasia, short philtrum, and macrognathia).
He was a portrait of the broken American male: insecure, anxious, and depressed, faced with the stark truth that all of the money and fame in the world cannot save him from himself.
Watching Europe sink into recession – and Greece plunge into the abyss – I found myself wondering what it would take to convince the chattering classes that austerity in the face of an already depressed economy is a terrible idea.
From the point of the euro area as a whole, fiscal policy has been dramatically and destructively "procyclical" — that is governments have slashed spending and raised taxes in the face of a deeply depressed economy.
As Paul Krugman wrote on his blog this weekend: "Watching Europe sink into recession – and Greece plunge into the abyss – I found myself wondering what it would take to convince the chattering classes that austerity in the face of an already depressed economy is a terrible idea".
What planet am I living on?" – The ECB, which bought totally into the doctrine of expansionary austerity, despite overwhelming evidence that it was false, and proceeded to raise rates in the face of a deeply depressed economy — possibly the straw that breaks the euro's back.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com