Sentence examples for fa pathway from inspiring English sources

FA mice have been used to study the role of the FA pathway in haematopoietic homeostasis.

Animal experiments have provided evidence for the protective role of the FA pathway in the detoxification of aldehyde compounds.

Molecular studies have shown that an intact FA pathway is necessary to restrict the HPV life cycle.

The Fanconi Anaemia (FA) pathway is a repair pathway devoted to repairing DNA inter-strand crosslinks (ICL) [10].

According to these studies, a functional FA pathway is required for the proper elimination of DNA damage induced by acetaldehyde.

Here we found that hRad18 can also regulate activation of the FA pathway.

The FA pathway-deficient cells are also hypersensitive to Chk1 silencing, 100) which may be explained by the hyperdependence of the FA pathway-deficient cells on G2/M checkpoint activation mediated by Chk1 for viability.

Inhibition of ATM in such FA pathway-deficient cells will leave no alternative mechanism for repair, leading to cell death.

Effect of inhibiting the BRCA/FA pathway.

Our objective was to investigate the role of the BRCA/FA pathway in BTC, focusing on several key molecules in the BRCA/FA pathway.

The BRCA/FA pathway was upregulated by GEM and cisplatin (CDDP) exposure.