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Unfortunately, her visual acuity remained poor given the chronicity of her disease and continued to decline in her right eye secondary to cataract progression.
However, our patient presented with a very severe retinal vasculitis at the posterior pole involving all the major branches of the central retinal vein in the right eye and a retinal vein occlusion in the left eye secondary to tubercular vasculitis which is a rare manifestation.
This may be a reflection of the reduced laser energy per burn reaching the eye secondary to its shorter duration.
Nine eyes (30%) were treated with trabeculectomy: 2 eyes with MMC 1 eye with β-irradiation, 1 eye secondary trabeculectomy with MMC after 19 years, and 2 eyes requiring transscleral cyclodiode laser.
Trauma was the leading cause for anophthalmic surgery in 40%% of cases followed by a blind painful eye secondary to glaucoma (19 %) in the enucleation group and endophthalmitis (28.6 %) in the evisceration group.
The most common cause of anophthalmic surgery in our series was trauma in 40%% of cases followed by a blind painful eye secondary to absolute glaucoma with phthisis bulbi and degeneration in the enucleation group and endophthalmitis in the evisceration group.
Similar(53)
Early neovascular complications are seen in these eyes secondary to ocular hypoxia as in our case where we treated our patient with multiple intravitreal injections of bevacizumab (Avastin,Genentech) which is a nonselective vascular endothelial growth factor inhibitor providing relief from pain till the eye was enucleated.
In 22 eyes secondary IOP rise was seen after a mean period of 7.8 ± 4.5 weeks.
19 of 22 eyes (86.36%) had complications, including cataract (10 eyes), secondary glaucoma (8 eyes), corneal leucoma or oedema (8 eyes), retinal detachment (8 eyes), strabismus (3 eyes) and nystagmus (2 eyes).
For both worse and study eyes, secondary efficacy endpoints included IOP change from baseline to weeks 1, 2, and 3, analyzed using the PP population, and percentage change in IOP at 8 a.m. 4 weeks postbaseline, analyzed using both the PP and the ITT populations.
Results: One hundred twenty-six children (204 eyes) were studied: infantile glaucoma, 52 eyes; aphakic glaucoma, 40 eyes; syndrome associated, 69 eyes; and secondary glaucoma, 43 eyes.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com