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Pax6 and its Drosophila homolog Eyeless (Ey) play essential roles during eye development.
However, the role of ey is not restricted to eye development.
The same gene, for example, that triggers eye development in fruit flies also triggers eye development in mice.
Whether 3-D imaging technology hurts eye development has implications well beyond Nintendo.
The embryonic phase of eye development is indicated by blue background.
The postembryonic phase of eye development is indicated by red background.
Pax6 is an evolutionary conserved transcription factor and is indispensable for eye development.
The increased shh expression had the pleiotropic consequence of leading to decreased eye development.
Using this network, we found network motifs, cis-regulatory codes, and regulators of eye development.
PAX6, a paired box transcription factor, is necessary for eye development.
They are, therefore, considered as master genes of eye development.
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