An instrument constructed with this improved wavefront sensor technique may provide a faster and more effective correction for the mouse eye aberrations using AO.
With the present work we are confident that the obstacle posed by aberrations can be overcome by using adaptive optics, which is especially beneficial for individual eye aberrations, and that an important step towards fs-vitreo-retinal surgery has been made.
We speculate that one of the major inputs into the chaotic dynamics of the eyes' aberrations is the effect of the heartbeat.
This is the splinter in the eye, an aberration that would be airbrushed out of a commercial photo shoot.
To our knowledge this is the first in vivo measurement of the mouse eye chromatic aberration.
The current in vivo measurement and previous estimations of the mouse eye chromatic aberration are summarized in Table 2 >.
If the only significant difference between mouse and rat eyes is a linear scale difference of two times, the mouse eye chromatic aberration should be two times as large as that of the rat eye.
Since infrared illumination was employed for measuring the eye's aberrations, it was necessary to correct for the existing chromatic aberration [ 31, 32].
A custom-developed Adaptive Optics (AO) system, including a Hartmann-Shack sensor and an electromagnetic deformable mirror, to measure and correct the eye's aberrations, and a phase-only reflective Spatial Light Modulator, to simulate the phase designs, was developed for this study.
Both studies showed a good correspondence between measured and computed eye's aberrations in a customized eye model that took into consideration the IOL´s tilt and decentration.
