1 The practice of performing extremity perfusions for sarcomas ended after Rosenberg showed the effectiveness of adjuvant radiation treatment in limb salvage.
1 One of the simplest and most useful parameters to objectively assess lower extremity arterial perfusion, and thus diagnose PAD, is the Ankle-Brachial Index (ABI).
Tissue viability was assessed for each extremity throughout the perfusion period as follows: perfusate samples were taken from the radial vein after 4 h and 8 h of perfusion to determine glucose utilization, lactate production, and lactate dehydrogenase (LDH) release.
Physeal stress injuries are thought to develop when repetitive loading of the extremity disrupts metaphyseal perfusion which in turn inhibits ossification of the chondrocytes in the zone of provisional calcification [ 101].
For numerous or unresectable in-transit metastases of the extremities, isolated limb perfusion or infusion with melphalan should be considered.
Objectives: We conducted the present study to assess the risk factors of inadequate perfusion of extremities during the vasopressors treatment in patients with severe septic shock.
Based on the 2011 WHO diagnostic criteria, shock was defined as lowering of pulse pressure to 20 mmHg or less or the presence of signs of poor capillary perfusion (cold extremities, poor capillary refill or a rapid pulse rate) [ 3].
In their patient, Boerma and colleagues [ 25] further observed clinically evident hypoperfusion of the distal extremities, a decreased peripheral perfusion index, as well as a substantial increase in the central-to-toe temperature difference (from 1.7 to 13.4°C) after terlipressin injection.
