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Improvements in the quality attributes of an RA (e.g., reuse, maintainability, security) are extremely difficult to evaluate in an analytic and quantitative fashion contrary to the efficacy of the business (e.g., sales) (Carriere et al. [2010]).
However, when data from various sources are combined as in the multi-source water balance modelling approach driven by satellite data, it becomes extremely difficult to evaluate and eliminate all of the uncertainties associated with data and models.
Usually, miRNA binds to multiple mRNA targets [88, 89] and, by such binding, can "label" mRNA to be degraded or translated into protein in an attenuated fashion making it extremely difficult to evaluate the importance of charges in expression [88, 90].
It is extremely difficult to evaluate the health of our workplace culture because objectionable conversations rarely occur in the open.
Complete response is seldom achieved via TACE and the presence of residual vital tumour is extremely difficult to evaluate.
It is extremely difficult to evaluate the accuracy of peak calling because of the lack of 'true' binding-site data.
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Its value is extremely difficult to measure experimentally.
Unfortunately, parallaxes are extremely difficult to measure.
Preliminary work with codon models has proven computationally difficult as the rate matrix is extremely large and difficult to evaluate [matrix exponentiation used in calculating probabilities of transitions is cubic at best with respect to the number of dimensions (Stoer et al., 2002) using eigen decomposition].
For this reason, scientists think that it is extremely difficult to separately evaluate the relative strength and importance of these currents in generating the particular modes of global or local magnetic disturbances that are to be studied in detail.
Sanders said she believes the fire is not actively spreading, although she noted it's difficult to evaluate the fire's reach because of "extremely restricted" visibility.
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CEO of Professional Science Editing for Scientists @ prosciediting.com