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In the face of rapid change and limited data, it is extremely challenging to predict what the Antarctic will do in the future.
Such deleterious effects are extremely challenging to predict due to the inherent complexity of immune function in vivo.
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The deformation behavior of metal lattice structures is extremely complex and challenging to predict, especially since strain is not uniformly distributed throughout the structure.
It is extremely difficult to predict the outcomes of macroeconomic events and even more challenging to predict how those events will impact financial markets.
The scale and pace of change are particularly challenging to predict.
At the same time, catastrophic outcomes can be very challenging to predict.
However, for many applications it remains challenging to predict system-level colloidal behavior.
"Rapidly deepening winter storms are very challenging to predict," the NWS wrote on its Facebook page.
58, 59 Patient response to oral antihyperglycemia drugs can be variable and challenging to predict.
It remains challenging to predict the outcomes of therapy in patients with rheumatoid arthritis (RA).
This is reasonable since it is very challenging to predict structures for a low-homology target.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com