Sentence examples for extremely challenging question from inspiring English sources

A final important, and extremely challenging, question pertains to the contribution of PABP1-mediated regulation of both default deadenylation/mRNA stabilization and mRNA-specific decay to mammalian physiology.

Just a reporter asking difficult, challenging questions.

Those startups face challenging questions.

He faced friendly crowds — and challenging questions.

Ask challenging questions and explain slowly.

Future studies exploring these questions would be welcome, although achieving the necessary statistical power would be extremely challenging.

It can be extremely challenging.

Making such a detection is extremely challenging.

Give Me Your Love is extremely challenging to perform.

The international dimension of investigating the world wide web especially has proved extremely challenging".

Public access to the Hudson River, the subject of "No River Wide Enough" (June 27), is extremely challenging.