Sentence examples for extreme differentiation from inspiring English sources

The eye lens presents a unique opportunity to explore roles for specific molecules in cell proliferation, differentiation and development because cells remain in place throughout life and, like red blood cells and keratinocytes, they go through the most extreme differentiation, including removal of nuclei and cessation of protein synthesis.

Moreover, rodents show one of the most extreme differentiation of the masticatory apparatus with a single pair of upper and lower incisors highly specialized for gnawing, and a small number of cheek teeth for chewing in association with the development of antero-posterior movements [2].

Whilst this had no impact on our results because permethrin resistance did not co-segregate with 2La inversion karyotype, the extreme differentiation between karyotypes in parts of this region (as reported previously [38]) could be problematic for other populations or phenotypes, and some method of stratified or corrected association testing may be required [48].

PRL cells are of extreme differentiation and most PRLomas are mono-hormonal.

Cell viability, cell cycle, SEM and microarray analysis data confirm the extreme differentiation process towards cellular death.

The selective scenario fits well within the finding that the regions that most strongly covaried with height distributions showed extreme differentiation.

Although statistical tests have been developed in order to identify loci showing more or less population differentiation than predicted under neutrality [ 24- 27], the exact form of the selection responsible for extreme differentiations is hardly ever addressed.

We generated artificial sets of SNPs with extreme allelic differentiation bias based on geographical sampling with cases from only one continent (BMD: n = 9, FCR: n = 8, GR: n = 25 and ROT: n = 18).

In addition to the extreme population differentiation at rs3827760, the unusual haplotype structure surrounding this SNP has been interpreted as evidence of recent positive selection at this locus in East Asia [17], [18], [19], [20].

According to strict selection, we used these 5,155 genes with extreme remarkable differentiation and uniquely described information to annotate the relative protein or transcript of these pathways, which was expected to describe the variation of gene expression in relative biological pathways.

The extreme population differentiation in this region is indicative of strong artificial selection.