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Since the follow-up period lasts one year and no extrapolation over time will be executed, discounting of costs is not necessary.
This part of the analysis will involve extrapolation over time and as such will be subject to more than just sampling variability.
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Thus, forecasts of expected immigration from these countries are a double extrapolation exercise – over time and across space.
Since this is a double extrapolation exercise – over time and across space – we have to invoke some identification assumptions that must hold to ensure that the forecasts are valid.
"People change over time.
Modelling the effects of pMTCT components 1 and 2 may demand more complex forms of model capable of capturing the dynamics of infection and transmission in the general population, as well as more comprehensive data permitting extrapolation over longer time horizons.
In a broader sense, even robust molecular biomarkers would underlie regulation networks, which would render extrapolation of effects over time difficult.
Even smaller sets of data, such as the recordings of budding and blossom times kept (1851 58) by American naturalist Henry David Thoreau in Concord, Mass., have been patched together with other records to create extrapolations of change over time.
Unfortunately, given the available follow-up in the clinical trials, survival data is often censored and therefore the expected survival cannot be obtained without extrapolation of the data over time.
We separated the prediction of toxicity over time from the extrapolation from one to many species and from acute to sublethal effects.
Here, we separated the three dimensions and addressed the prediction of toxicity over time separately from the extrapolation to many species and sublethal effects.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com