We can provide a crude estimate of the number of potentially untreated patients over the age of 75 years by linear extrapolation of the population rate for RRT from 1790 pmp at 75 years to 2500 pmp for the age group 100 years.
The fluid pressure at the inlet and the outlet of the flow domain is specified by spatial extrapolation of particle populations.
Our study provides novel data that can be used in decision analyses and cost effectiveness studies to inform clinical practice guidelines, which to date have relied on extrapolations of general population data.
Again, the extrapolation of densities to population size at a larger scale must account for possible limitations related to the survey design and effort invested.
Due to the absence of other ethnic groups in our population, extrapolation of our results to outpatient populations should be done with caution.
Inappropriate extrapolation of results to populations (e.g., Medicaid) not included in the original study.
We have previously acknowledged uncertainties related to the extrapolation of CRFs across populations, which we have attempted to minimize by applying CRFs, asthma prevalence, and outcome frequency estimates for Southern California, when available (Künzli et al. 2008).
However, the availability of high-quality country-level data on 2 major host risk factors for iNTS (i.e., HIV and malaria [ 6 ]) provides a basis for extrapolation of the few population-based iNTS surveillance data that are available for other areas.
However, due to the fact that the Correlation Type being fulfilled is B and not A (which means that the result is valid for at least 75%% of the driver population), any extrapolation of the results to the general population should be done with some reservation.
Third, as our subjects were recruited from eight hospitals in São Paulo, Brazil, they may not necessarily be representative of the general Brazilian population, and thus any extrapolation of results to the general population should be done cautiously.
