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The possible role of these agents is theoretical and is based on extrapolation of evidence available for patients receiving rivaroxaban.
55 The optimal choice of chemotherapeutic agent in HIPEC is unclear and is probably based on extrapolation of evidence from the efficacy of intravenous chemotherapy.
Economic evaluations in middle income countries like Mexico often require extrapolation of evidence and assumptions from other countries or from regional databases.
As such, extrapolation of evidence from other contexts is problematic, and this paper contributes importantly to our emergent understanding of adolescent pregnancy in the Sri Lankan setting.
The result for those over 18 was not unexpected given the audit was undertaken before the Australian guidelines [ 4], which include 'good practice points' recommending extrapolation of evidence for those up to the age of 25, were released.
Escitalopram and citalopram may be beneficial options in treating anxiety disorders in HCV based upon the anecdotal reports of safety in HCV [ 43- 45] and extrapolation of evidence from non-HCV anxiety treatment guidelines [ 46].
Similar(53)
Supporters of extrapolation suggest that extrapolation of scientific evidence should be seen as a logical consequence of the comparability exercise principle, which is founded in physiochemical and biological characterization.
To date, no randomised trial has examined the role of anti-fungal prophylaxis in patients with severe acute pancreatitis and practice guidelines must thus be based on extrapolation of current evidence.
Although this can be justified by extrapolation of the evidence from the PROWESS trial, practical critical care management in this setting must not overlook the need to rule out infection of necrosis, and must further be cognisant of the specific risks of haemorrhage in patients with prolonged pancreatitis and pancreatic necrosis.
The extrapolation of available evidences for probiotics to preterm neonates should take into account the characteristics of the products utilized and of the population included in the examined studies.
Extreme caution is required to avoid over-extrapolation of the evidence leading to damage to vulnerable services for people with high unmet need but potential to benefit.
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CEO of Professional Science Editing for Scientists @ prosciediting.com