Sentence examples for extrapolated to human from inspiring English sources
Moreover, quantitative data can be either modeled to predict cumulative drug effects which can be further extrapolated to human settings to provide insights into drug action previously undetectable.
While the results can't be directly extrapolated to human health, the research nonetheless paves the way for additional studies on the relative health benefits of organic versus conventionally grown foods.
ERG photoresponses performed similarly in humans and animals may provide a common ground for interspecies comparison of dysfunction and allow the outcomes of potential forms of treatment applied to animal models to be extrapolated to human patients.
The findings of our work clearly demonstrate that interspecies simulations can be employed to design animal tests a priori so that the results can be effectively and efficiently extrapolated to human conditions in a meaningful manner.
FIGURES: Left: Changes in proportions of cerebral cortical areas that are most directly linked to peripheral sensory and motor systems that have resulted from human brain expansion, in percent of prediction for a typical ape brain extrapolated to human proportions (from The Symbolic Species).
Thus, these results can not be extrapolated to human heart.
The basis for these findings is the hazard posed by increased particle surface area for a given mass of small-sized particles, as derived from animal studies and extrapolated to humans.
We also posit that the "mouse variability distribution" may be further extrapolated to humans using the PBPK model and the resulting human variability distribution may be compared with available data on the variability of the human pharmacokinetics of TCE to determine whether the mouse-derived distribution is consistent with the human evidence.
Thus, the researcher is frequently left with the dilemma of which animal model(s) most accurately represent(s) and reproduce(s) the human condition being investigated (if any), and to what extent the results obtained from these models can be correctly and predictably extrapolated to humans.
Dosimetry calculations revealed that In-DOTA[Ahx-Lys]exendin-4 resulted in the highest effective dose (extrapolated to humans, 155 μSv/MBq), whereas the effective dose of Ga-DOTA[Ahx-Lys]exendin-4 and 99mTc-EDDA/HYNIC [Ahx-Lys]exendin-4 were much lower (32 μSv/MBq and 3.7 μSv/MBq, respectively).
In the current work, the biodistribution and pharmacokinetics of 64Cu-MM-302 were investigated in mice and extrapolated to estimate human dosimetry.
