First, because the Hunter New England community is a well- defined population with a limited number of hospitals where persons with acute respiratory illness are hospitalized, HNEPH was able to implement population-based surveillance for acute respiratory illness hospitalizations and deaths, eliminating the need to extrapolate estimates from a limited sample of the population.
Because bicycle ridership is quite variable across regions, it is impossible to extrapolate estimates of the epidemiological burden.
Recently, the risk assessment and atmospheric modeling communities have recognized the importance of developing approaches to extrapolate estimates from other studies in situations where input data are limited or comprehensive models are impractical.
Use your own logical methods to extrapolate estimates for market sizing.
If an extrapolated estimate violates a constraint, it could be a valuable indication that the model is inappropriate when applied to all the studies.
Using these latter estimates to extrapolate, our estimate would fall to somewhat over 100 unintentional gun deaths per year to children.
Extrapolating estimates of true and false positive rates at this probability, about 11,000 genes, more than half the large set of genes tested, are predicted to have a highly redundant paralog.
As 2 Mb represents ∼1/1500 of the genome we extrapolated estimates for the number of independent variants for the circulating biomarkers (all and split by minor allele frequency bin) multiplying by 1500.
We calculated the number of NoV GE cases in high-income (HI) and upper-middle income (UMI) countries for NoV outpatient visits, hospitalizations and deaths among older adults by extrapolating estimated incidence rates to cumulative HI and UMI country population figures for those ≥65 years based on 2013 World Bank population estimates (http://data.worldbank.org).org
Firstly, due to the absence of patient level empirical comparative study covering a time span consistent with the assumed survival horizon for MBC patients, the Markov model extrapolated estimates for 5-year OS and PFS, as well as costs for both nab-paclitaxel and conventional paclitaxel from the results of a pivotal comparative trial.
