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The slight differences in shape of the resulting prions would alter their biochemistry enough to produce the distinct sets of symptoms that accompany different strains.An extraordinary hypothesis, you might think.
This extraordinary hypothesis may have been built upon the earlier work by Means regarding the potential treatment of thyroid disease using external X-rays [3].
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If the true hypothesis is comparatively implausible, the plausibility assessments merely slow down the rate at which it comes to dominate its rivals, reflecting the idea that extraordinary hypotheses require extraordinary evidence (or an extraordinary accumulation of evidence) to overcome their initial implausibilities.
This indeed supports my hypothesis that extraordinary, unremitting endurance exercise can injure a normal heart.
Although this kind of "evidence" may not be representable via evidential likelihoods (because the hypotheses it bears on don't deductively or probabilistically imply it), it often plays an important role in scientific assessments of hypotheses — in assessments of whether a hypothesis is so extraordinary that only really extraordinary likelihood evidence could rescue it.
Bailey considers claims made against Blanchard's theory extraordinary, and extraordinary claims require extraordinary proof.
"But such a hypothesis probably constitutes an extraordinary claim, and it should undergo more scrutiny before it is allowed to enter the field".
An extraordinary claim arises from this "niche hypothesis": the healthier the habitat, the more "musical" the creatures, the richer and more diverse their scores.
A fascinating hypothesis to explain the extraordinary expansion of TEs in the genome of T. vaginalis was proposed by Carlton and collaborators [ 9]. T. vaginalis, unlike most other Trichomonads which are enteric, is a parasite of the human urogenital tract.
Here, a hypothesis is presented that the extraordinary performance of the cortex derives from an associative mechanism built in at the cellular level to the basic cortical neuronal unit: the pyramidal cell.
The lead author believed that the extensive WHI data would be sufficient to give reliably valid results and extraordinary efforts were made to confirm this hypothesis.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com