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Their extraordinary gene expression divergence was unexpected given an average coding sequence divergence of about 3% [ 22], and represents the greatest divergence reported to date among congeneric plant species [ 16, 23].
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The transcriptional mechanisms that underlie this extraordinary restriction in gene expression remain unclear.
Exploration of DGE data and microfluidic qPCR analyses at individual level showed an extraordinary polymorphism in gene expressions, but also a set of hemocyte-expressed genes whose basal mRNA levels discriminate oyster capacity to survive infections by the pathogenic V. splendidus LGP32.
Genome-wide expression studies transformed the field of transcriptomics and made it feasible to study global gene expression in extraordinary detail.
RNA interference (RNAi) offers an attractive means to silence gene expression with extraordinary specificity, particularly for the subset of candidate therapeutic gene targets that are considered "undruggable".
We revealed an extraordinary interindividual polymorphism in basal gene expression that is associated to an inherent capacity of some oysters to survive Vibrio infections.
Besides, we show here for the first time an extraordinary individual polymorphism of hemocyte basal gene expression in oysters.
We showed that the metabolic switch is a sophisticated mechanism of transcriptional regulation capable of resetting and re-synchronizing gene expression programs at extraordinary speed and scale.
Viral miRNAs can be extraordinary tools to modulate cellular or viral gene expression.
In addition, variation in gene expression further contributes to the extraordinary phenotypic diversity and plasticity of maize.
Gamete development in the absence of de-novo P5CR gene expression could rely upon the extraordinary stability of the P5CR protein.
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