A cry signal recording can thus be thought of being composed of what we call the regions of interest, namely, expiratory and inspiratory phases, and extraneous regions consisting the rest of the audio activity contained in the recording, termed as residual in this paper.
Reads in these extraneous regions were not considered in variant detection.
We progressively vary the length of the extraneous flanking region (L f ℓ ), which refers to the combined length of the left and right flanking segments around the motif location.
In a cry analysis system meant to work with recordings captured in realistic environments, there is often a need for a pre-processing system which is able to differentiate the regions of interest (i.e., expiratory and inspiratory phases) from extraneous acoustic regions (i.e., residual).
To obtain sequences with extraneous flanking regions, we had to separately download genome segments (around the motifs in Rfam) from GenBank with appropriate additional flanking.
Also, given that we use extraneous flanking regions around the motif occurrences in input sequences, folding such sequences may not make realistic sense in some cases.
This allows visualization of the specific pathway connecting 2 regions without extraneous connectivity to other regions.
This increases the sensitivity and rejects extraneous noise, especially important in regions of turbulence.
It is resistant to the common problem of extraneous or "non-informative" promoter regions included in the co-regulated set.
Second, decomposing PPI networks into spatially- and temporally-coherent subnetworks (DECOMP [ 10]) addresses the problem of complexes embedded in highly-connected regions with many extraneous edges.
Compared to littermate controls, we did not observe any changes in either HC or SGN density in Sema3f −/− cochleae, suggesting the extraneous SGN processes in the OHC region are not a secondary effect of other cochlear changes.
