Ahr and Ahr-eGFP coding sequences were extracted from the construct pEGFP-Ahr (provided by Dr. P. Fernandez-Salguero) and cloned into XbaI in pUASt.
In the step of feature extraction, weighted local clustering coefficients of each ROI in relation to the remaining ROIs are extracted from all the constructed brain networks to quantify the prevalence of clustered connectivity around the ROIs.
The approach started with identification of multiple disease pathways, called a gene forest, in which the genes extracted from the decision forest constructed by supervised learning of the genome-wide transcriptional profiles for patients and normal samples.
The expression profiles of those genes related to apoptosis and autophagy, including MCL1, BCL2, ATG, beclin-1, BAX, BAK, E2F, cMYC, PI3K, AKT, BAD, and LC3, were extracted from the dataset to construct the gene networks.
The subtrees were extracted from trees constructed using the maximum-likelihood method.
Herein, a database termed the Multiple Target Ligand Database (MTLD, www.mtdcadd.com) based on 3D structural data extracted from the PDB has been constructed.
To evaluate the ability of the candidate miRNAs extracted from two constructed miRNAs interaction networks for discriminating breast cancer subtype, we defined two miRNA groups: one is the miRNAs group with the common hub miRNAs shared by two constructed miRNAs interaction networks and the other is the miRNAs group with 201 differentially expressed miRNAs.
Next, invariant moments and geometric characteristics of time-frequency distribution of mD signatures are extracted from the segmented spectrogram to construct mD feature vectors.
In this paragraph we explain the-low level attributes that are extracted from the audio signals for constructing statistical models which represent the basic a priori knowledge we have about the audio categories.
