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Each file (n = 2,869) was parsed using a Perl script to extract gene expression matrix and metadata.
Specifically, the multi-mgMOS (multi-chip modified gamma model for oligonucleotide signal) model was used to extract gene expression levels and their estimated uncertainties [20].
In the preliminary result, the baseline method can extract gene expression more precisely than other methods that extract the key entities or verbs only in sentences.
The high scalability and low maintenance cost of the unsupervised patterns could help our system to extract gene expression from PubMed abstracts more precisely and effectively.
The goal of this work is to develop an unsupervised pattern generation module and use these patterns to extract gene expression relationships from literature for gene regulatory network construction.
Several EST-based tools have been developed to extract gene expression profiles.
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In addition, we used an analytical program developed at the National Institute of Environmental Health Sciences (NIEHS), EPIG (extracting gene expression patterns and identifying co-expressed genes), to identify patterns of gene expression that differed between the liver and kidney (Zhou et al. 2006).
To identify gene changes likely to be related to toxicity, we analyzed genes on the basis of their temporal pattern of change using a program developed at the National Institute of Environmental Health Sciences, termed "EPIG" (extracting gene expression patterns and identifying co-expressed genes).
In this paper, we therefore aim to reduce the cost of manual rules for extracting gene expression relationships.
Xenbase curation processes centre on associating papers with genes and extracting gene expression patterns.
We extracted gene expression data from the GEO database with accession number GDS2545.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com