Data extraction Two reviewers extracted data concerning study methods, pharmacological intervention with acetazolamide, method of assessment of acute mountain sickness, and event rates in both control and intervention groups, which were verified and analysed by the review team collaboratively.
Data Extraction: Two reviewers independently extracted data concerning trial methods, quality, and outcomes.
Two reviewers independently extracted data concerning participant characteristics, intervention details (including participants' lithium exposure immediately preceding the trial), and outcome measures from the included studies.
Two reviewers (C.B. and A.C). independently extracted data concerning participant characteristics, intervention details and outcome measures.
Based on the expanded IPDAS checklist for users [ 39], we therefore extracted data concerning these additional components.
Two review authors independently extracted data concerning details of the study population, interventions and outcomes using a standard data extraction form, specifically designed for this review.
We extracted data concerning prescription of drugs to lower blood pressure and cholesterol concentration in the 90 days before the query date.
To determine the location of ZmPP genes on 10 chromosomes, we extracted data concerning gene positions from the Maize Genome Sequence Project.
Finally, we extracted data concerning the reporting of results including the type of endpoint (eg, binary vs continuous), effect size and measure of variance, use of other methods to report results (eg, probability of treatment being best, claims of equivalence or non-inferiority) and the format/presentation of results (eg, text, tables and figures).
Extracted data concerned the incidence, gender distribution, age, external causes, C-T lesions, associated injuries, early transfer and mortality at the end of acute hospitalization.
