Sentence examples for extracellular matrix elements from inspiring English sources

It is also likely that the TIF contains peptides deriving from extracellular matrix elements cleaved by matrix metalloproteases known to be active in the tumor interstitium [28], [29].

Functional analysis revealed a prominent presence of genes encoding proteases and protease inhibitors, cell adhesion molecules, extracellular matrix elements and cytoskeletal molecules potentially related to tubular restructuring and changes in cell junction dynamics.

In the search for tumor specific biomarkers the focus should accordingly be on the tumor interstitial environment and the secretome and thus in the fluid phase bathing the tumor cells and the extracellular matrix elements, i.e. in the tumor interstitial fluid (TIF) [6].

MV has been shown to activate extracellular matrix elements such as collagen and proteoglycan [ 32].

Cluster-113 peptide has a cysteine scaffold found in the cysteine rich region of tick salivary metalloproteases, suggestive of an interaction with extracellular matrix elements.

Another hypothesis has suggested that T cells might use extracellular matrix elements such as the fibroblastic reticular cell network [ 35] as a guidance system for T cell migration [ 36].

Moreover, the role of cell-extracellular matrix elements interactions in the regulation of expression and activity of MMPs and their inhibitors was analyzed by culturing these cell lines on plastic or on artificial ECM (Matrigel).

Transcript levels of integrin subunits that mediate cell adhesion to these extracellular matrix (ECM) elements were determined by real-time RT PCR.

Matrix metallo-proteinases, a family of zinc-dependent metallo-endopeptidases, are involved in the degradation of the extracellular matrix, a central element of tumor invasion and metastasis.

Proper function of the BBB has been shown to rely critically on the sustained interaction with the adjacent extracellular matrix components and cellular elements [ 9].

Derivatives of galactose in glycoconjugates are key elements of cell membrane structures, hormones, extracellular matrix, immunologic determinants and structural elements of the central nervous system, among other roles (Segal, 1995).